Therapeutic effects of novel resin bonding systems containing bioactive glasses on mineral-depleted areas within the bonded-dentine interface

Salvatore Sauro*, Raquel Osorio, Timothy F. Watson, Manuel Toledano

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

115 Citations (Scopus)

Abstract

This study aimed in evaluating the effects of two experimental resin bonding systems containing conventional Bioglass 45S5 (BAG) or Zinc-polycarboxylated bioactive glass (BAG-Zn) micro-fillers on the resin-bonded dentine interface after storage in a simulated body fluid solution (SBFS). Three resin bonding systems were formulated: Resin-A: (BAG containing); Resin-B; (BAG-Zn containing); Resin-C (no filler). The ability of the experimental resins to evoke apatite formation was evaluated using confocal Raman spectroscopy. Acid-etched dentine specimens were bonded, and prepared for AFM/nano-indentation analysis in a fully-hydrated status to evaluate the modulus of elasticity (Ei) and hardness (Hi) across the interface at different SBFS storage periods. Further resin-dentine specimens were tested for microtensile bond strength after 24 h or 3 months of SBFS storage. SEM examination was performed after de-bonding and confocal laser microscopy was used to evaluate the ultramorphology of the interfaces and micropermeability. The resin A and B showed a consistent presence of apatite (967 cm(-1)), reduced micropermeability within the resin-dentine interface and a significant increase of the Ei and Hi along the bonded-dentine interface after prolonged SBFS storage. Bond strength values were affected by the resin system ( <0.0001) and by storage time ( <0.0001) both after 24 h and 3 months of SBFS storage. In conclusion, resin bonding systems containing bioactive fillers may a have therapeutic effect on the nano-mechanical properties and sealing ability of mineral-depleted resin-dentine interface.

Original languageEnglish
Pages (from-to)1521-1532
Number of pages12
JournalJournal of Materials Science: Materials in Medicine
Volume23
Issue number6
DOIs
Publication statusPublished - Jun 2012

Keywords

  • DEMINERALIZED HUMAN DENTIN
  • MECHANICAL-PROPERTIES
  • COLLAGEN
  • DEGRADATION
  • HYBRID LAYERS
  • ADHESIVES
  • CALCIUM-PHOSPHATE CEMENT
  • IN-VIVO
  • MATRIX METALLOPROTEINASES
  • BIOMIMETIC REMINERALIZATION

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