Abstract
Reliable temperature information during clinical hyperthermia and thermal ablation is essential for adequate treatment control, but conventional temperature measurements do not provide 3D temperature information. Treatment planning is a very useful tool to improve treatment quality, and substantial progress has been made over the last decade. Thermal modelling is a very important and challenging aspect of hyperthermia treatment planning. Various thermal models have been developed for this purpose, with varying complexity. Since blood perfusion is such an important factor in thermal redistribution of energy in in vivo tissue, thermal simulations are most accurately performed by modelling discrete vasculature. This review describes the progress in thermal modelling with discrete vasculature for the purpose of hyperthermia treatment planning and thermal ablation. There has been significant progress in thermal modelling with discrete vasculature. Recent developments have made real-time simulations possible, which can provide feedback during treatment for improved therapy. Future clinical application of thermal modelling with discrete vasculature in hyperthermia treatment planning is expected to further improve treatment quality.
| Original language | English |
|---|---|
| Pages (from-to) | 336-345 |
| Number of pages | 10 |
| Journal | International Journal of Hyperthermia |
| Volume | 29 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Jun 2013 |
Keywords
- Ablation
- Discrete vasculature
- Hyperthermia
- Hyperthermia treatment planning
- Optimisation
- RF heating
