Tissue viability (TiVi) imaging: temporal effects of local occlusion studies in the volar forearm

Paul McNamara, James O'Doherty, Marie-Louise O' Connell, Barry Fitzgerald, Chris Anderson, Gert Nilsson, Rani Toll, Martin Leahy

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Tissue Viability (TiVi) imaging is a promising new technology for the assessment of microcirculation in the upper human dermis. Although the technique is easily implemented and develops large amounts of observational data, its role in the clinical workplace awaits the development of standardised protocols required for routine clinical practice. The present study investigates the use of TiVi technology in a human, in vivo, localized, skin blood flow occlusion protocol. In this feasibility study, the response of the cutaneous microcirculation after provocation on the volar surface of the forearm was evaluated using a high temporal-low spatial resolution TiVi camera. 19 healthy subjects - 10 female and 9 male - were studied after a localized pressure was applied for 5 different time periods ranging from 5 to 25 seconds. Areas corresponding to 100 x 100 pixels (2.89 cm(2)) were monitored for 60 seconds prior to, during and after each occlusion period. Our results demonstrated the removal of blood from the local area and a hyperaemic response supporting the suitability of TiVi imaging for the generation of detailed provocation response data of relevance for the physiological function of the skin microcirculation in health and disease.
Original languageEnglish
Pages (from-to)66-74
Number of pages9
JournalJournal of biophotonics
Volume3
Issue number1-2
DOIs
Publication statusPublished - Jan 2010

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