Towards ultrathin fiber-optic probe for simultaneous photoacoustic and fluorescence endoscopy

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Abstract

A dual-modal photoacoustic and fluorescence endoscopy probe based on a single multimode fiber with a diameter of 140m was developed. By using a digital micromirror device with a high-speed algorithm for modulating the incident optical wavefront, the light transmission distortion through a multimode fiber was characterized and thus a focused laser beam was scanned at the distal fiber tip for microscopy imaging. Evaluation of the imaging performance was conducted with a dual-modal phantom comprising carbon fibers and fluorescence beads, and mouse red blood cells. The imaging probe has the potential to be further miniaturized using a fiber-optic ultrasound sensor so that it could be integrated into surgical tools such as medical needles for the guidance of minimally invasive procedures.

Original languageEnglish
Title of host publication2021 IEEE International Ultrasonics Symposium (IUS)
PublisherIEEE
Pages1-4
Number of pages4
DOIs
Publication statusPublished - 16 Nov 2021

Publication series

NameIEEE International Ultrasonics Symposium, IUS
PublisherI E E E
ISSN (Print)1948-5719

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