King's College London

Research portal

Towards ultrathin fiber-optic probe for simultaneous photoacoustic and fluorescence endoscopy

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

Original languageEnglish
Title of host publication2021 IEEE International Ultrasonics Symposium (IUS)
PublisherIEEE
Pages1-4
Number of pages4
DOIs
Published16 Nov 2021

Publication series

NameIEEE International Ultrasonics Symposium, IUS
PublisherI E E E
ISSN (Print)1948-5719

Bibliographical note

Funding Information: This project was supported by the Academy of Medical Sciences/the Wellcome Trust/ the Government Department of Business, Energy and Industrial Strategy/the British Heart Foundation/Diabetes UK Springboard Award [SBF006/1136], Wellcome Trust (203148/Z/16/Z, WT101957) and Engineering and Physical Sciences Research Council (NS/A000027/1, NS/A000049/1). Publisher Copyright: © 2021 IEEE.

Documents

  • Letter_2

    Letter_2.pdf, 1.31 MB, application/pdf

    Uploaded date:18 Nov 2021

    Version:Accepted author manuscript

King's Authors

Abstract

A dual-modal photoacoustic and fluorescence endoscopy probe based on a single multimode fiber with a diameter of 140m was developed. By using a digital micromirror device with a high-speed algorithm for modulating the incident optical wavefront, the light transmission distortion through a multimode fiber was characterized and thus a focused laser beam was scanned at the distal fiber tip for microscopy imaging. Evaluation of the imaging performance was conducted with a dual-modal phantom comprising carbon fibers and fluorescence beads, and mouse red blood cells. The imaging probe has the potential to be further miniaturized using a fiber-optic ultrasound sensor so that it could be integrated into surgical tools such as medical needles for the guidance of minimally invasive procedures.

Download statistics

No data available

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454