Transaortic Transcatheter Aortic Valve Implantation Using Edwards SAPIEN Valve: A Novel Approach

TY - JOUR

T1 - Transaortic Transcatheter Aortic Valve Implantation Using Edwards SAPIEN Valve

T2 - A Novel Approach

AU - Bapat, Vinayak

AU - Khawaja, Muhammed

AU - Attia, Rizwan

AU - Narayana, Ashok

AU - Wilson, Karen

AU - Macgillivray, Kirsty

AU - Young, Christopher

AU - Hancock, Jane

AU - Redwood, Simon

AU - Thomas, Martyn

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Objectives: To evaluate feasibility and outcome of Transoartic Transcatheter Sapien valve implantation. Background: Transcatheter Aortic valve implantation (TAVI) using the Edwards SAPIEN device (Edwards LifeScience, Irvine, CA) is usually performed via the transfemoral (TF) or transapical (TA) routes. Some patients are not suitable for these approaches. We report our experience with the novel transaortic (TAo) approach via a partial upper sternotomy and discuss the advantages and future applications. Methods: Between January 2008 to March 2011 193 patients with severe aortic stenosis underwent TAVI with the Edwards SAPIEN bioprosthesis at the St. Thomas' Hospital, London. 108 patients were unable to undergo a TF-TAVI and of those 17 were accepted for a TAo-TAVI on the basis of anatomy, risk, LV function, and significant respiratory disease. Results: The TAo-TAVI group (n = 17) had more prevalent respiratory disease than the TA-TAVI group (47.0% vs. 18.7%, P = 0.011). Otherwise the groups were similar in demographics and history. Despite this the 30 day mortalities were not significantly different between the groups (TAo-TAVI 4.3% at 30 days versus TA-TAVI 7.7%, P = 0.670). There were no significant differences in procedural complications. Conclusions: The TA-TAVI approach may not be desirable in patients with severe chest deformity, poor lung function or poor left ventricular function. TAo-TAVI via a partial sternotomy is safe and feasible in these patients.

AB - Objectives: To evaluate feasibility and outcome of Transoartic Transcatheter Sapien valve implantation. Background: Transcatheter Aortic valve implantation (TAVI) using the Edwards SAPIEN device (Edwards LifeScience, Irvine, CA) is usually performed via the transfemoral (TF) or transapical (TA) routes. Some patients are not suitable for these approaches. We report our experience with the novel transaortic (TAo) approach via a partial upper sternotomy and discuss the advantages and future applications. Methods: Between January 2008 to March 2011 193 patients with severe aortic stenosis underwent TAVI with the Edwards SAPIEN bioprosthesis at the St. Thomas' Hospital, London. 108 patients were unable to undergo a TF-TAVI and of those 17 were accepted for a TAo-TAVI on the basis of anatomy, risk, LV function, and significant respiratory disease. Results: The TAo-TAVI group (n = 17) had more prevalent respiratory disease than the TA-TAVI group (47.0% vs. 18.7%, P = 0.011). Otherwise the groups were similar in demographics and history. Despite this the 30 day mortalities were not significantly different between the groups (TAo-TAVI 4.3% at 30 days versus TA-TAVI 7.7%, P = 0.670). There were no significant differences in procedural complications. Conclusions: The TA-TAVI approach may not be desirable in patients with severe chest deformity, poor lung function or poor left ventricular function. TAo-TAVI via a partial sternotomy is safe and feasible in these patients.

KW - TAVI

KW - aortic stenosis

KW - TAo

KW - minimally invasive

KW - mini sternotomy

KW - POSTOPERATIVE PAIN

KW - ASCENDING AORTA

KW - SOURCE REGISTRY

KW - STENOSIS

KW - DISEASE

KW - ARTERY

KW - INTERVENTION

KW - REPLACEMENT

KW - COMPLICATIONS

KW - THORACOTOMY

U2 - 10.1002/ccd.23276

DO - 10.1002/ccd.23276

M3 - Article

SN - 1522-1946

VL - 79

SP - 733

EP - 740

JO - CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

JF - CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

IS - 5

ER -