Transcatheter atrial septal defect closure guided by colour flow Doppler

Aphrodite Tzifa, Justin Gordon, Shane Tibby, Eric Rosenthal, Shakeel Qureshi

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)


    Objectives: To describe and assess the use of the maximum colour flow diameter (CFDmax) in guiding transcatheter closure of atrial septal defects (ASDs) and compare it with the standard balloon sizing method.

    Background: Balloon sizing of ASDs has been the standard method of assessing the size of ASDs and selecting a closure device. However, overestimation of the defect by stretching it may result in complications such as erosion of the atrial wall or aortic root, particularly in the presence of a deficient aortic rim and the long-term effects of oversized defects are unknown.

    Methods: Retrospective and prospective assessment of 115 consecutive patients who underwent ASD closure during three different time periods, when change in local practice occurred. Fifty patients underwent ASD closure with balloon sizing (period A), 15 with the aid of balloon sizing and additional estimation of the CFDmax (period B) and 50 with sole assessment of the CFDmax (period C).

    Results: The mean difference between the device used and the 2D defect size decreased from 6.9 to 5.1 mm (p

    Conclusions: Transcatheter closure of ASDs guided solely by the CFDmax is feasible and safe and results in decreased procedure and screening times, whilst maintaining a low complication rate.

    Original languageEnglish
    Pages (from-to)299-303
    Number of pages5
    JournalInternational Journal of Cardiology
    Issue number3
    Publication statusPublished - 16 Jun 2011


    • Atrial septal defect
    • Transcatheter closure
    • Interventional cardiology
    • Amplatzer septal occluder
    • ADULTS
    • SIZE


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