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Transcatheter coil occlusion of the arterial duct - Results of the European Registry

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A G Magee, I C Huggon, P T Seed, S A Qureshi, M Tynan, Association for European Paediatric Cardiology

Original languageEnglish
Pages (from-to)1817 - 1821
Number of pages5
JournalEuropean Heart Journal
Issue number19
Publication statusPublished - 2001

King's Authors


Aims To report on the data, collected by the Association for European Paediatric Cardiology (AEPC) Registry, on transcatheter coil occlusion of the arterial duct. Methods and Results A retrospective study was conducted of intention-to-treat data from 30 European and Middle Eastern tertiary referral centres which included an analysis of causes of suboptimal outcome. Since 1994, reports have been made on 1291 attempted coil occlusions of the arterial duct in 1258 patients. Median age at procedure was 4 years (range 0.1 52) and median weight was 29 kg (range 1.8-100). Following coil implantation, the immediate occlusion rate was 59%, which rose to 95 lo at 1 year. A suboptimal outcome occurred on 129 occasions (10% of procedures) and was defined as coil embolization, an abandoned procedure, persistent haemolysis, residual leak requiring a further procedure, flow impairment in adjacent structures and duct re-canalization. A number of clinical factors were chosen but only increasing duct size [odds ratio of 2-6:1 (CI 2-3,2)] and the presence of a tubular shaped duct [odds ratio 2.4:1 (CI 1-4-4)] were positively associated with an unfavourable outcome. Conclusion The results of the European Registry support the view that transcatheter coil occlusion of the persistent arterial duct is a safe and effective procedure. Unfavourable outcomes are more likely when closing larger and/or tubular shaped ducts. (C) 2001 The European Society of Cardiology.

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