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Transcriptome analysis of Pseudomonas aeruginosa growth: Comparison of gene expression in planktonic cultures and developing and mature biofilms

Research output: Contribution to journalArticle

Richard D. Waite, Anastasia Papakonstantinopoulou, Eddie Littler, Michael A. Curtis

Original languageEnglish
Pages (from-to)6571-6576
Number of pages6
JournalJournal of Bacteriology
Issue number18
Publication statusPublished - Sep 2005

King's Authors


The transcriptomes of logarithmic- and stationary-phase Pseudomonas aeruginosa planktonic cultures and static biofilms of different stages of development were compared. Developing and confluent biofilm transcriptomes were found to be related to those of logarithmic- and stationary-phase planktonic cultures, respectively. In addition, a number of novel genes were up-regulated in developing and confluent biofilms, including genes encoding putative solute transport proteins and transcriptional regulators, respectively.

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