Treatment of allergic children – Where is the progress (for the practicing allergist)?

TY - JOUR

T1 - Treatment of allergic children – Where is the progress (for the practicing allergist)?

AU - Wert, A.F.

AU - Posa, D.

AU - Tsilochristou, O.

AU - Schwerk, N.

N1 - Export Date: 31 October 2018

PY - 2016/11

Y1 - 2016/11

N2 - For any kind of therapeutic intervention in allergic diseases such as environmental control, pharmacological, or immunomodulating treatment including educational programs, children are addressed separately from adults. Health authorities like the Food and Drug Administration in the United States of America or the European Medicine Agency in Europe request a specific ‘Pediatric investigational plan’ with studies addressing dose–response relationship, safety, and efficacy for infants, children, and adolescents. During the last 2 years, promising advances have been reported for the treatment of a variety of allergic and immunologic disorders. This review summarizes the progress in the treatment of pediatric asthma and allergic diseases, based on publications of approximately the last 2.5 years (end of 2013 until May 2016) in and beyond this journal. Meanwhile, it highlights areas with promising novel therapeutic approaches, which are likely to change treatment for allergic children in the near future.

AB - For any kind of therapeutic intervention in allergic diseases such as environmental control, pharmacological, or immunomodulating treatment including educational programs, children are addressed separately from adults. Health authorities like the Food and Drug Administration in the United States of America or the European Medicine Agency in Europe request a specific ‘Pediatric investigational plan’ with studies addressing dose–response relationship, safety, and efficacy for infants, children, and adolescents. During the last 2 years, promising advances have been reported for the treatment of a variety of allergic and immunologic disorders. This review summarizes the progress in the treatment of pediatric asthma and allergic diseases, based on publications of approximately the last 2.5 years (end of 2013 until May 2016) in and beyond this journal. Meanwhile, it highlights areas with promising novel therapeutic approaches, which are likely to change treatment for allergic children in the near future.

U2 - 10.1111/pai.12653

DO - 10.1111/pai.12653

M3 - Article

SN - 0905-6157

VL - 27

SP - 671

EP - 681

JO - Pediatric Allergy and Immunology

JF - Pediatric Allergy and Immunology

IS - 7

ER -