TY - CHAP
T1 - Treatment of Thrombosis in Antiphospholipid Syndrome
AU - Ruiz-Irastorza, Guillermo
AU - Khamashta, Munther
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Thromboses are among the most severe manifestations of antiphospholipid syndrome (APS), particularly those affecting cerebral arteries. Thus, correct management of thrombotic complications is paramount to improving the prognosis of patients with antiphospholipid antibodies (aPL). In fact, the ideal approach would be to prevent patients with aPL from developing full APS (ie, to keep them asymptomatic). Unfortunately, on many occasions, the clinical event comes first, and it is then that we notice the presence of aPL. We all agree that whatever the clinical scenario – patients with thrombosis or asymptomatic aPL carriers – every effort must be made to prevent clotting events. However, the optimal treatment regimes are sometimes a matter of intense debate.
AB - Thromboses are among the most severe manifestations of antiphospholipid syndrome (APS), particularly those affecting cerebral arteries. Thus, correct management of thrombotic complications is paramount to improving the prognosis of patients with antiphospholipid antibodies (aPL). In fact, the ideal approach would be to prevent patients with aPL from developing full APS (ie, to keep them asymptomatic). Unfortunately, on many occasions, the clinical event comes first, and it is then that we notice the presence of aPL. We all agree that whatever the clinical scenario – patients with thrombosis or asymptomatic aPL carriers – every effort must be made to prevent clotting events. However, the optimal treatment regimes are sometimes a matter of intense debate.
KW - anticoagulants
KW - antiphospholipid antibodies
KW - Antiphospholipid syndrome
KW - thrombosis
UR - http://www.scopus.com/inward/record.url?scp=85045917408&partnerID=8YFLogxK
U2 - 10.1016/B978-0-444-63655-3.00016-8
DO - 10.1016/B978-0-444-63655-3.00016-8
M3 - Chapter
AN - SCOPUS:85045917408
T3 - Handbook of Systemic Autoimmune Diseases
SP - 231
EP - 241
BT - Handbook of Systemic Autoimmune Diseases
PB - Elsevier Ltd
ER -