Treatment of Thrombosis in Antiphospholipid Syndrome

Guillermo Ruiz-Irastorza, Munther Khamashta

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Thromboses are among the most severe manifestations of antiphospholipid syndrome (APS), particularly those affecting cerebral arteries. Thus, correct management of thrombotic complications is paramount to improving the prognosis of patients with antiphospholipid antibodies (aPL). In fact, the ideal approach would be to prevent patients with aPL from developing full APS (ie, to keep them asymptomatic). Unfortunately, on many occasions, the clinical event comes first, and it is then that we notice the presence of aPL. We all agree that whatever the clinical scenario – patients with thrombosis or asymptomatic aPL carriers – every effort must be made to prevent clotting events. However, the optimal treatment regimes are sometimes a matter of intense debate.

Original languageEnglish
Title of host publicationHandbook of Systemic Autoimmune Diseases
PublisherElsevier Ltd
Pages231-241
Number of pages11
DOIs
Publication statusPublished - 1 Jan 2017

Publication series

NameHandbook of Systemic Autoimmune Diseases
Volume12
ISSN (Print)1571-5078

Keywords

  • anticoagulants
  • antiphospholipid antibodies
  • Antiphospholipid syndrome
  • thrombosis

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