Type IV pilus: one architectural problem, many structural solutions

Julien R C Bergeron; Nikolaos G Sgourakis

doi:10.1016/j.str.2015.01.004

Type IV pilus: one architectural problem, many structural solutions

Julien R C Bergeron, Nikolaos G Sgourakis

Randall Centre of Cell & Molecular Biophysics

National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA. Electronic address: [email protected].

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

Type IV pili are long appendages found at the surface of many bacteria, composed of an oligomerized pilin protein and involved in processes such as adherence, motility and DNA transfer. In this issue of Structure, Piepenbrink and colleagues report the first structure a major pilin from a Gram-positive bacterium, revealing an unprecedented stabilization mechanism that may have implications for pilus evolution.

Original language	English
Pages (from-to)	253-5
Number of pages	3
Journal	Structure
Volume	23
Issue number	2
DOIs	https://doi.org/10.1016/j.str.2015.01.004
Publication status	Published - 3 Feb 2015

Keywords

Clostridium difficile/chemistry
Evolution, Molecular
Fimbriae, Bacterial/chemistry
Models, Molecular

Access to Document

10.1016/j.str.2015.01.004

Cite this

@article{b8045cf67b7e467586febb4bae4882a8,

title = "Type IV pilus: one architectural problem, many structural solutions",

abstract = "Type IV pili are long appendages found at the surface of many bacteria, composed of an oligomerized pilin protein and involved in processes such as adherence, motility and DNA transfer. In this issue of Structure, Piepenbrink and colleagues report the first structure a major pilin from a Gram-positive bacterium, revealing an unprecedented stabilization mechanism that may have implications for pilus evolution. ",

keywords = "Clostridium difficile/chemistry, Evolution, Molecular, Fimbriae, Bacterial/chemistry, Models, Molecular",

author = "Bergeron, {Julien R C} and Sgourakis, {Nikolaos G}",

year = "2015",

month = feb,

day = "3",

doi = "10.1016/j.str.2015.01.004",

language = "English",

volume = "23",

pages = "253--5",

journal = "Structure",

issn = "0969-2126",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - Type IV pilus

T2 - one architectural problem, many structural solutions

AU - Bergeron, Julien R C

AU - Sgourakis, Nikolaos G

PY - 2015/2/3

Y1 - 2015/2/3

N2 - Type IV pili are long appendages found at the surface of many bacteria, composed of an oligomerized pilin protein and involved in processes such as adherence, motility and DNA transfer. In this issue of Structure, Piepenbrink and colleagues report the first structure a major pilin from a Gram-positive bacterium, revealing an unprecedented stabilization mechanism that may have implications for pilus evolution.

AB - Type IV pili are long appendages found at the surface of many bacteria, composed of an oligomerized pilin protein and involved in processes such as adherence, motility and DNA transfer. In this issue of Structure, Piepenbrink and colleagues report the first structure a major pilin from a Gram-positive bacterium, revealing an unprecedented stabilization mechanism that may have implications for pilus evolution.

KW - Clostridium difficile/chemistry

KW - Evolution, Molecular

KW - Fimbriae, Bacterial/chemistry

KW - Models, Molecular

U2 - 10.1016/j.str.2015.01.004

DO - 10.1016/j.str.2015.01.004

M3 - Article

C2 - 25651057

SN - 0969-2126

VL - 23

SP - 253

EP - 255

JO - Structure

JF - Structure

IS - 2

ER -

Type IV pilus: one architectural problem, many structural solutions

Abstract

Keywords

Access to Document

Fingerprint

Cite this