UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016

D. Creamer, Sheilagh Patricia Mary Walsh, P. Dziewulski, L.S. Exton, H.Y. Lee, J.K.G. Dart, J. Setterfield, C.B. Bunker, M.R. Ardern-Jones, K.M.T. Watson, G.A.E. Wong, M. Philippidou, A. Vercueil, R.V. Martin, G. Williams, M. Shah, D. Brown, P. Williams, M.F. Mohd Mustapa, C.H. Smith

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Abstract

Summary
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease. The document aims to:∗ offer an appraisal of all relevant literature up to February 2016, focusing on any key developments. ∗ address important, practical clinical questions relating to the primary guideline objective, i.e. accurate diagnosis and identification of cases and suitable treatment. ∗ provide guideline recommendations. ∗ discuss areas of uncertainty, potential developments and future directions.
Original languageEnglish
Pages (from-to)e119–e153
JournalJournal of Plastic Reconstructive and Aesthetic Surgery
Volume69
Issue number6
Early online date7 May 2016
DOIs
Publication statusPublished - Jun 2016

Keywords

  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • drug hypersensitivity
  • management
  • guidelines

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