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Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides

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Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides. / Anselmi, Silvia; Aggarwal, Nandini; Moody, Thomas S.; Castagnolo, Daniele.

In: ChemBioChem, 01.01.2020.

Research output: Contribution to journalReview article

Harvard

Anselmi, S, Aggarwal, N, Moody, TS & Castagnolo, D 2020, 'Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides', ChemBioChem. https://doi.org/10.1002/cbic.202000430

APA

Anselmi, S., Aggarwal, N., Moody, T. S., & Castagnolo, D. (Accepted/In press). Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides. ChemBioChem. https://doi.org/10.1002/cbic.202000430

Vancouver

Anselmi S, Aggarwal N, Moody TS, Castagnolo D. Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides. ChemBioChem. 2020 Jan 1. https://doi.org/10.1002/cbic.202000430

Author

Anselmi, Silvia ; Aggarwal, Nandini ; Moody, Thomas S. ; Castagnolo, Daniele. / Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides. In: ChemBioChem. 2020.

Bibtex Download

@article{a33ae564228d4e23b62f325907ab2b9d,
title = "Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides",
abstract = "Sulfoxides are a class of organic compounds that find wide application in medicinal and organic chemistry. Several biocatalytic approaches have been developed to synthesise enantioenriched sulfoxides, mainly by exploiting oxidative enzymes. Recently, the use of reductive enzymes such as Msr and Dms has emerged as a new, alternative method to obtain enantiopure sulfoxides from racemic mixtures. In parallel, novel oxidative approaches, employing nonclassical solvents such as ionic liquids (ILs) and deep eutectic solvents (DESs), have been developed as greener and more sustainable biocatalytic synthetic pathways. This minireview aims highlights the recent advances made in the biocatalytic synthesis of enantioenriched sulfoxides by employing such unconventional approaches.",
keywords = "biocatalysis, deep eutectics, ionic liquids, reductive enzymes, sulfoxides",
author = "Silvia Anselmi and Nandini Aggarwal and Moody, {Thomas S.} and Daniele Castagnolo",
year = "2020",
month = jan,
day = "1",
doi = "10.1002/cbic.202000430",
language = "English",
journal = "Chembiochem : a European journal of chemical biology",
issn = "1439-4227",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides

AU - Anselmi, Silvia

AU - Aggarwal, Nandini

AU - Moody, Thomas S.

AU - Castagnolo, Daniele

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Sulfoxides are a class of organic compounds that find wide application in medicinal and organic chemistry. Several biocatalytic approaches have been developed to synthesise enantioenriched sulfoxides, mainly by exploiting oxidative enzymes. Recently, the use of reductive enzymes such as Msr and Dms has emerged as a new, alternative method to obtain enantiopure sulfoxides from racemic mixtures. In parallel, novel oxidative approaches, employing nonclassical solvents such as ionic liquids (ILs) and deep eutectic solvents (DESs), have been developed as greener and more sustainable biocatalytic synthetic pathways. This minireview aims highlights the recent advances made in the biocatalytic synthesis of enantioenriched sulfoxides by employing such unconventional approaches.

AB - Sulfoxides are a class of organic compounds that find wide application in medicinal and organic chemistry. Several biocatalytic approaches have been developed to synthesise enantioenriched sulfoxides, mainly by exploiting oxidative enzymes. Recently, the use of reductive enzymes such as Msr and Dms has emerged as a new, alternative method to obtain enantiopure sulfoxides from racemic mixtures. In parallel, novel oxidative approaches, employing nonclassical solvents such as ionic liquids (ILs) and deep eutectic solvents (DESs), have been developed as greener and more sustainable biocatalytic synthetic pathways. This minireview aims highlights the recent advances made in the biocatalytic synthesis of enantioenriched sulfoxides by employing such unconventional approaches.

KW - biocatalysis

KW - deep eutectics

KW - ionic liquids

KW - reductive enzymes

KW - sulfoxides

UR - http://www.scopus.com/inward/record.url?scp=85090469975&partnerID=8YFLogxK

U2 - 10.1002/cbic.202000430

DO - 10.1002/cbic.202000430

M3 - Review article

C2 - 32735057

AN - SCOPUS:85090469975

JO - Chembiochem : a European journal of chemical biology

JF - Chembiochem : a European journal of chemical biology

SN - 1439-4227

ER -

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