Uncovering neurodevelopmental features in bipolar affective disorder

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Abstract

Schizophrenia and bipolar disorder are genetically related and their clinical features overlap. Schizophrenia is conceptualised as a neurodevelopmental disorder but the evidence for bipolar disorder is less clear. Cluster-analytic approaches reveal different cognitive profiles within bipolar disorder, possibly reflective of differing neurodevelopmental loads, which are also suggested by recent genetic and neuroimaging studies. Such studies suggest the potential utility of further clinical subcategories in bipolar disorder based on neurodevelopmental load. Declaration of interest None.

Original languageEnglish
Pages (from-to)383-385
Number of pages3
JournalBritish Journal of Psychiatry
Volume215
Issue number1
Early online date22 May 2019
DOIs
Publication statusPublished - 1 Jul 2019

Keywords

  • Bipolar affective disorders
  • aetiology
  • developmental disorders
  • psychotic disorders
  • schizophrenia

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