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Understanding the influence of personality traits on risk of suicidal behaviour in schizophrenia spectrum disorders: A systematic review

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Manuel Canal-Rivero, Rosa Ayesa-Arriola, Esther Setién-Suero, Benedicto Crespo-Facorro, Celso Arango, Rina Dutta, Javier David Lopez-Morinigo

Original languageEnglish
Article number4604
JournalJournal of Clinical Medicine
Volume10
Issue number19
DOIs
Published1 Oct 2021

Bibliographical note

Funding Information: Funding: This study was supported by the Universidad Autónoma de Madrid (Spain) and European Union via the Intertalentum Project Grant-Marie Skłodowska Curie Actions (GA 713366) to J.-D.L.-M., which also funded the APC. R.A.-A. acknowledges funding support from the Spanish Carlos III Health Institute via a Miguel Servet grant which covers her salary (CP18/00003), which is being carried out at Fundación Instituto de Investigación Marqués de Valdecilla (Santander, Spain). E.S.-S.’s salary comes from the Spanish Agencia Estatal de Investigación via a Juan de la Cierva Training grant (FJC2019–042390-I/AEI/10.13039/501100011033). CA was supported by the Spanish Ministry of Science and Innovation. Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024), cofinanced by ERDF Funds from the European Commission, “A way of making Europe”, CIBERSAM. Madrid Regional Government (B2017/BMD-3740 AGES-CM-2), European Union Structural Funds. European Union Seventh Framework Program under grant agreements FP7-4-HEALTH-2009-2.2.1-2-241909 (Project EU-GEI), FP7-HEALTH-2013-2.2.1-2-603196 (Project PSYSCAN) and FP7-HEALTH-2013-2.2.1-2-602478 (Project METSY); and European Union H2020 Program under the Innovative Medicines Initiative 2 Joint Undertaking (grant agreement No 115916, Project PRISM, and grant agreement No 777394, Project AIMS-2-TRIALS), Fundación Familia Alonso and Fundación Alicia Koplowitz. M.C.-R., works as Clinical Psychologist at Virgen del Rocío University Hospital (Seville, Spain) via Consejería de Salud y Familias (Junta de Andalucía) 2020 grant which covers his salary (RH-0081-2020). Funding Information: This study was supported by the Universidad Aut?noma de Madrid (Spain) and European Union via the Intertalentum Project Grant-Marie Sk?odowska Curie Actions (GA 713366) to J.-D.L.-M., which also funded the APC. R.A.-A. acknowledges funding support from the Spanish Carlos III Health Institute via a Miguel Servet grant which covers her salary (CP18/00003), which is being carried out at Fundaci?n Instituto de Investigaci?n Marqu?s de Valdecilla (Santander, Spain). E.S.-S.?s salary comes from the Spanish Agencia Estatal de Investigaci?n via a Juan de la Cierva Training grant (FJC2019?042390-I/AEI/10.13039/501100011033). CA was supported by the Spanish Ministry of Science and Innovation. Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024), co-financed by ERDF Funds from the European Commission, ?A way of making Europe?, CIBERSAM. Madrid Regional Government (B2017/BMD-3740 AGES-CM-2), European Union Structural Funds. European Union Seventh Framework Program under grant agreements FP7-4-HEALTH-2009-2.2.1-2-241909 (Project EU-GEI), FP7-HEALTH-2013-2.2.1-2-603196 (Project PSYSCAN) and FP7-HEALTH-2013-2.2.1-2-602478 (Project METSY); and European Union H2020 Program under the Innovative Medicines Initiative 2 Joint Undertaking (grant agreement No 115916, Project PRISM, and grant agreement No 777394, Project AIMS-2-TRIALS), Fundaci?n Familia Alonso and Fundaci?n Alicia Koplowitz. M.C.-R., works as Clinical Psychologist at Virgen del Roc?o University Hospital (Seville,We acknowledge departmental support from our institutions mentioned above. Spain) via Consejer?a de Salud y Familias (Junta de Andaluc?a) 2020 grant which covers his salary (RH-0081-2020). Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

King's Authors

Abstract

Risk of suicidal behaviour (SB) in schizophrenia spectrum disorders (SSD) is a major concern, particularly in early stages of the illness, when suicide accounts for a high number of premature deaths. Although some risk factors for SB in SSD are well understood, the extent to which personality traits may affect this risk remains unclear, which may have implications for prevention. We conducted a systematic review of previous studies indexed in MEDLINE, PsycINFO and Embase examining the relationship between personality traits and SB in samples of patients with SSD. Seven studies fulfilled predetermined selection criteria. Harm avoidance, passive-dependent, schizoid and schizotypal personality traits increased the risk of SB, while self-directedness, cooperativeness, excluding persistence and self-transcendence acted as protective factors. Although only seven studies were retrieved from three major databases after applying predetermined selection criteria, we found some evidence to support that personality issues may contribute to SB in patients with SSD. Personality traits may therefore become part of routine suicide risk assessment and interventions targeting these personality-related factors may contribute to prevention of SB in SSD.

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