Unveiling the Spectrum of Glucose Variability: A Novel Perspective on FreeStyle Libre Monitoring Data

TY - JOUR

T1 - Unveiling the Spectrum of Glucose Variability: A Novel Perspective on FreeStyle Libre Monitoring Data

AU - Heald, Adrian H

AU - Stedman, Mike

AU - Warner-Levy, John

AU - Belston, Lleyton

AU - Paisley, Angela

AU - Jotic, Aleksandra

AU - Lalic, Nebojsa

AU - Gibson, Martin

AU - Habte-Asres, Hellena

AU - Whyte, Martin

AU - Forbes, Angus

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/12

Y1 - 2024/12

N2 - IntroductionSince the introduction of insulin therapy, it has become apparent that type 1 diabetes (T1D) is accompanied by long-term microvascular and macrovascular complications. In the context of the many benefits of continuous glucose monitoring (CGM), there remain opportunities to study the large amount of data now available in order to maximise its potential in the endeavour to reduce the occurrence of diabetes tissue complications in the longer term.MethodsContinuous glucose monitoring values were downloaded for 89 type 1 diabetes mellitus (T1D) individuals for up to 18 months from 2021 to 2023. Data for patient demographics was also taken from the patient record which included Sex, Date of Birth, and Date of Diagnosis. The recorded laboratory glycated haemoglobin (HbA1c) test results were also recorded. The glucose management index (GMI) was calculated from average glucose readings for 18 months using the formula GMI (%) = (0.82 − (Average glucose/100)). This was then adjusted to give GMI (mmol/mol

AB - IntroductionSince the introduction of insulin therapy, it has become apparent that type 1 diabetes (T1D) is accompanied by long-term microvascular and macrovascular complications. In the context of the many benefits of continuous glucose monitoring (CGM), there remain opportunities to study the large amount of data now available in order to maximise its potential in the endeavour to reduce the occurrence of diabetes tissue complications in the longer term.MethodsContinuous glucose monitoring values were downloaded for 89 type 1 diabetes mellitus (T1D) individuals for up to 18 months from 2021 to 2023. Data for patient demographics was also taken from the patient record which included Sex, Date of Birth, and Date of Diagnosis. The recorded laboratory glycated haemoglobin (HbA1c) test results were also recorded. The glucose management index (GMI) was calculated from average glucose readings for 18 months using the formula GMI (%) = (0.82 − (Average glucose/100)). This was then adjusted to give GMI (mmol/mol

UR - http://www.scopus.com/inward/record.url?scp=85207188343&partnerID=8YFLogxK

U2 - 10.1007/s13300-024-01647-x

DO - 10.1007/s13300-024-01647-x

M3 - Article

SN - 1869-6953

VL - 15

SP - 2475

EP - 2487

JO - Diabetes Therapy

JF - Diabetes Therapy

IS - 12

ER -