Urothelial malignant disease and Chinese herbal nephropathy

G M Lord; T Cook; Volker M. Arlt; H H Schmeiser; G Williams; C D Pusey

doi:10.1016/S0140-6736(01)06576-X

Urothelial malignant disease and Chinese herbal nephropathy

G M Lord, T Cook, Volker M. Arlt, H H Schmeiser, G Williams, C D Pusey

Research output: Contribution to journal › Letter › peer-review

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Abstract

We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) In two patients In the UK. These cases highlighted the role of aristolochic acid In causing this nephropathy, which was first described In a Belgian cohort. We now report development of invasive transitional cell carcinoma of the! urinary tract associated with the presence of aristolochic acid-DNA adducts In one of these patients. This work clearly shows the carcinogenic potential of aristolochic acid In this new type of nephropathy

Original language	English
Pages (from-to)	1515 - 1516
Number of pages	2
Journal	The Lancet
Volume	358
Issue number	9292
DOIs	https://doi.org/10.1016/S0140-6736(01)06576-X
Publication status	Published - 3 Nov 2001

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title = "Urothelial malignant disease and Chinese herbal nephropathy",

abstract = "We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) In two patients In the UK. These cases highlighted the role of aristolochic acid In causing this nephropathy, which was first described In a Belgian cohort. We now report development of invasive transitional cell carcinoma of the! urinary tract associated with the presence of aristolochic acid-DNA adducts In one of these patients. This work clearly shows the carcinogenic potential of aristolochic acid In this new type of nephropathy",

author = "Lord, {G M} and T Cook and Arlt, {Volker M.} and Schmeiser, {H H} and G Williams and Pusey, {C D}",

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T1 - Urothelial malignant disease and Chinese herbal nephropathy

AU - Lord, G M

AU - Cook, T

AU - Arlt, Volker M.

AU - Schmeiser, H H

AU - Williams, G

AU - Pusey, C D

PY - 2001/11/3

Y1 - 2001/11/3

N2 - We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) In two patients In the UK. These cases highlighted the role of aristolochic acid In causing this nephropathy, which was first described In a Belgian cohort. We now report development of invasive transitional cell carcinoma of the! urinary tract associated with the presence of aristolochic acid-DNA adducts In one of these patients. This work clearly shows the carcinogenic potential of aristolochic acid In this new type of nephropathy

AB - We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) In two patients In the UK. These cases highlighted the role of aristolochic acid In causing this nephropathy, which was first described In a Belgian cohort. We now report development of invasive transitional cell carcinoma of the! urinary tract associated with the presence of aristolochic acid-DNA adducts In one of these patients. This work clearly shows the carcinogenic potential of aristolochic acid In this new type of nephropathy

U2 - 10.1016/S0140-6736(01)06576-X

DO - 10.1016/S0140-6736(01)06576-X

M3 - Letter

SN - 1474-547X

VL - 358

SP - 1515

EP - 1516

JO - The Lancet

JF - The Lancet

IS - 9292

ER -

Urothelial malignant disease and Chinese herbal nephropathy

Abstract

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