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Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)235-241
JournalBritish Journal of Oral and Maxillofacial Surgery
Volume55
Issue number3
Early online date24 Dec 2016
DOIs
StatePublished - Apr 2017

King's Authors

Abstract

Radiation-induced fibrosis in the head and neck is a well-established pathophysiological process after radiotherapy. Recently pentoxifylline and tocopherol have been proposed as treatments to combat the late complications of radiation-induced fibrosis and a way of dealing with osteoradionecrosis. They both have a long history in the management of radiation-induced fibrosis at other anatomical sites. In this paper we review their use in sites other than the head and neck to illustrate the potential benefit that they offer to our patients.

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