King's College London

Research portal

Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)235-241
JournalBritish Journal of Oral and Maxillofacial Surgery
Issue number3
Early online date24 Dec 2016
Accepted/In press27 Nov 2016
E-pub ahead of print24 Dec 2016
PublishedApr 2017

King's Authors


Radiation-induced fibrosis in the head and neck is a well-established pathophysiological process after radiotherapy. Recently pentoxifylline and tocopherol have been proposed as treatments to combat the late complications of radiation-induced fibrosis and a way of dealing with osteoradionecrosis. They both have a long history in the management of radiation-induced fibrosis at other anatomical sites. In this paper we review their use in sites other than the head and neck to illustrate the potential benefit that they offer to our patients.

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454