Research output: Contribution to journal › Article › peer-review
Lee Jollans, Cao Zhipeng, Ilknur Icke, Ciara Greene, Clare Kelly, Tobias Banaschewski, Arun L W Bokde, Uli Bromberg, Christian Büchel, Anna Cattrell, Patricia J Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot & 8 more
Original language | English |
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Pages (from-to) | 1-16 |
Number of pages | 16 |
Journal | Developmental Neuropsychology |
Early online date | 13 Apr 2016 |
DOIs | |
Accepted/In press | 11 Mar 2016 |
E-pub ahead of print | 13 Apr 2016 |
Ventral striatum connectivity during_JOLLAN_Accepted 11Mar2016_GREEN AAM
Ventral_striatum_connectivity_during_JOLLAN_Accepted_11Mar2016_GREEN_AAM.pdf, 446 KB, application/pdf
Uploaded date:08 Jul 2016
Version:Accepted author manuscript
Ventral striatum connectivity during_JOLLAN_Accepted 11Mar2016_tables and figures_GREEN AAM
Ventral_striatum_connectivity_during_JOLLAN_Accepted_11Mar2016_tables_and_figures_GREEN_AAM.pdf, 574 KB, application/pdf
Uploaded date:08 Jul 2016
Version:Accepted author manuscript
Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.
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