Volume and shape preservation of enhancing lesions when applying non-rigid registration to a time series of contrast enhancing MR breast images

S L Delp (Editor), A M DiGioia, B Jaramaz (Editor), M J Clarkson, D Rueckert, D L G Hill, D J Hawkes

Research output: Chapter in Book/Report/Conference proceedingConference paper

66 Citations (Scopus)

Abstract

Shows that a non-rigid registration algorithm, which is used to register time-series MR images of the breast, can result in significant volume changes in the region of the enhanced lesion. Since this is physically implausible, given the short duration of the MR time-series acquisition, the non-rigid registration algorithm was extended to allow the incorporation of rigid regions. In this way, the registration is done in two stages. The enhanced lesions are first detected using the non-rigid registration algorithm in its original form. Secondly, the region of the enhanced lesion is set to be rigid and the new algorithm is applied to integrate this rigid region into the existing registration. By definition, volume and shape are preserved in this rigid region. Preliminary results of applying this algorithm to 15 data sets are described. (11 References).
Original languageEnglish
Title of host publicationConference Proceedings - Lecture Notes in Computer Science (LNCS) Vol# 1935
Place of PublicationBerlin, Germany
PublisherSpringer
Pages327 - 337
Number of pages11
ISBN (Print)3540411895
Publication statusPublished - 2000
EventMICCAI 2000: Medical Image Computing & Computer Assisted Intervention - 3rd International Conference - Pittsburgh, PA, United States
Duration: 11 Oct 200014 Oct 2000

Conference

ConferenceMICCAI 2000: Medical Image Computing & Computer Assisted Intervention - 3rd International Conference
Country/TerritoryUnited States
CityPittsburgh, PA
Period11/10/200014/10/2000

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