Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data

Miho Shidahara; Charalampos Tsoumpas; Colm McGinnity; Takashi Kato; Hajime Tamura; Alexander Hammers; Hiroshi Watabe; Federico E. Turkheimer

doi:10.1109/NSSMIC.2011.6152561

Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data

Miho Shidahara, Charalampos Tsoumpas, Colm McGinnity, Takashi Kato, Hajime Tamura, Alexander Hammers, Hiroshi Watabe, Federico E. Turkheimer

Tohoku University

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

Abstract

The purpose of this study was the evaluation of a wavelet-based resolution recovery (RR) method, named structural and functional synergy for RR (SFS-RR), for a variety of simulated human brain [C-11]raclopride PET images. Simulated datasets of 15 human phantoms were processed by SFS-RR using an anatomical prior. This anatomical information was in the form of a hybrid segmented-atlas, which combines an MRI for anatomical labelling and a PET image for functional labelling of each anatomical structure. First, the relationship between the FWHM of the original the PET image and its resolution recovered version was investigated. Then quantitative evaluation was performed by comparing caudate, putamen and cerebellum regions of the true image; simulated PET image; and RR image. The spatial resolution of the original PET image effected on how accurately SFS-RR recovers the image counts in striatum regions. The resolution in striatum, and cerebellum regions was successfully recovered for all the 15 human phantoms. The proposed methodology proved effective in the resolution recovery of small structures of brain [C-11]raclopride PET images. The improvement was consistent across the anatomical variability of a simulated population, provided accurate anatomical segmentations are available.

Original language	English
Title of host publication	2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
Place of Publication	NEW YORK
Publisher	IEEE
Pages	3097-3101
Number of pages	5
ISBN (Print)	978-1-4673-0120-6, 978-1-4673-0118-3
DOIs	https://doi.org/10.1109/NSSMIC.2011.6152561
Publication status	Published - 2011
Event	IEEE Nuclear Science Symposium/Medical Imaging Conference (NSS/MIC)/18th International Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors - Valencia Duration: 23 Oct 2011 → 29 Oct 2011

Conference

Conference	IEEE Nuclear Science Symposium/Medical Imaging Conference (NSS/MIC)/18th International Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors
City	Valencia
Period	23/10/2011 → 29/10/2011

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10.1109/NSSMIC.2011.6152561

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Shidahara, M., Tsoumpas, C., McGinnity, C., Kato, T., Tamura, H., Hammers, A., Watabe, H., & Turkheimer, F. E. (2011). Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data. In 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) (pp. 3097-3101). IEEE. https://doi.org/10.1109/NSSMIC.2011.6152561

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abstract = "The purpose of this study was the evaluation of a wavelet-based resolution recovery (RR) method, named structural and functional synergy for RR (SFS-RR), for a variety of simulated human brain [C-11]raclopride PET images. Simulated datasets of 15 human phantoms were processed by SFS-RR using an anatomical prior. This anatomical information was in the form of a hybrid segmented-atlas, which combines an MRI for anatomical labelling and a PET image for functional labelling of each anatomical structure. First, the relationship between the FWHM of the original the PET image and its resolution recovered version was investigated. Then quantitative evaluation was performed by comparing caudate, putamen and cerebellum regions of the true image; simulated PET image; and RR image. The spatial resolution of the original PET image effected on how accurately SFS-RR recovers the image counts in striatum regions. The resolution in striatum, and cerebellum regions was successfully recovered for all the 15 human phantoms. The proposed methodology proved effective in the resolution recovery of small structures of brain [C-11]raclopride PET images. The improvement was consistent across the anatomical variability of a simulated population, provided accurate anatomical segmentations are available.",

author = "Miho Shidahara and Charalampos Tsoumpas and Colm McGinnity and Takashi Kato and Hajime Tamura and Alexander Hammers and Hiroshi Watabe and Turkheimer, {Federico E.}",

year = "2011",

doi = "10.1109/NSSMIC.2011.6152561",

language = "English",

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booktitle = "2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)",

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Shidahara, M, Tsoumpas, C , McGinnity, C, Kato, T, Tamura, H, Hammers, A, Watabe, H & Turkheimer, FE 2011, Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data. in 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). IEEE, NEW YORK, pp. 3097-3101, IEEE Nuclear Science Symposium/Medical Imaging Conference (NSS/MIC)/18th International Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Valencia, 23/10/2011. https://doi.org/10.1109/NSSMIC.2011.6152561

Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data. / Shidahara, Miho; Tsoumpas, Charalampos ; McGinnity, Colm et al.
2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). NEW YORK: IEEE, 2011. p. 3097-3101.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

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T1 - Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data

AU - Shidahara, Miho

AU - Tsoumpas, Charalampos

AU - McGinnity, Colm

AU - Kato, Takashi

AU - Tamura, Hajime

AU - Hammers, Alexander

AU - Watabe, Hiroshi

AU - Turkheimer, Federico E.

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N2 - The purpose of this study was the evaluation of a wavelet-based resolution recovery (RR) method, named structural and functional synergy for RR (SFS-RR), for a variety of simulated human brain [C-11]raclopride PET images. Simulated datasets of 15 human phantoms were processed by SFS-RR using an anatomical prior. This anatomical information was in the form of a hybrid segmented-atlas, which combines an MRI for anatomical labelling and a PET image for functional labelling of each anatomical structure. First, the relationship between the FWHM of the original the PET image and its resolution recovered version was investigated. Then quantitative evaluation was performed by comparing caudate, putamen and cerebellum regions of the true image; simulated PET image; and RR image. The spatial resolution of the original PET image effected on how accurately SFS-RR recovers the image counts in striatum regions. The resolution in striatum, and cerebellum regions was successfully recovered for all the 15 human phantoms. The proposed methodology proved effective in the resolution recovery of small structures of brain [C-11]raclopride PET images. The improvement was consistent across the anatomical variability of a simulated population, provided accurate anatomical segmentations are available.

AB - The purpose of this study was the evaluation of a wavelet-based resolution recovery (RR) method, named structural and functional synergy for RR (SFS-RR), for a variety of simulated human brain [C-11]raclopride PET images. Simulated datasets of 15 human phantoms were processed by SFS-RR using an anatomical prior. This anatomical information was in the form of a hybrid segmented-atlas, which combines an MRI for anatomical labelling and a PET image for functional labelling of each anatomical structure. First, the relationship between the FWHM of the original the PET image and its resolution recovered version was investigated. Then quantitative evaluation was performed by comparing caudate, putamen and cerebellum regions of the true image; simulated PET image; and RR image. The spatial resolution of the original PET image effected on how accurately SFS-RR recovers the image counts in striatum regions. The resolution in striatum, and cerebellum regions was successfully recovered for all the 15 human phantoms. The proposed methodology proved effective in the resolution recovery of small structures of brain [C-11]raclopride PET images. The improvement was consistent across the anatomical variability of a simulated population, provided accurate anatomical segmentations are available.

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DO - 10.1109/NSSMIC.2011.6152561

M3 - Conference paper

SN - 978-1-4673-0120-6

SN - 978-1-4673-0118-3

SP - 3097

EP - 3101

BT - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

PB - IEEE

CY - NEW YORK

T2 - IEEE Nuclear Science Symposium/Medical Imaging Conference (NSS/MIC)/18th International Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors

Y2 - 23 October 2011 through 29 October 2011

ER -

Wavelet-based resolution recovery using anatomical prior provides quantitative recovery for human population phantom PET [C-11]raclopride data

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