Abstract

Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the last decade. In this perspective, we will summarize the current perspectives of the clinical application of both tolAPC and Treg, and will address future directions and the importance of immunomonitoring in clinical studies that will result in progress in the field.

Original languageEnglish
Article number181
Pages (from-to)181
Number of pages1
JournalFrontiers in Immunology
Volume10
Issue numberFEB
DOIs
Publication statusPublished - 22 Feb 2019

Keywords

  • autoimmunity
  • cell therapy
  • clinic
  • dendritic cells
  • immunomonitoring
  • regulatory T cells
  • tolerance
  • transplantation

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