Work Disability in Axial Spondyloarthritis

Elena Nikiphorou*, Sofia Ramiro

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)


Purpose of Review: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that typically affects people of working age. Work-related outcomes are therefore important to study, both from an individual but also a societal perspective. Through this review of the literature, we explore the impact of axSpA on key work outcomes including work and productivity loss and predictors for these. Recent Findings: Recent evidence confirms that axSpA is associated with substantial consequences on the ability to work. Reassuringly, early treatment and use of biologics have been associated with improved wok outcomes highlighting the importance of prompt diagnosis and management. High disease activity, labour-intensive jobs, poor physical function and impaired spinal mobility are among identified predictors of adverse work outcomes in axSpA. Summary: The impact of axSpA on work outcomes is considerable and necessitates optimal intervention, including suppression of disease activity, to enhance people’s chances of remaining in work.

Original languageEnglish
Article number55
JournalCurrent Rheumatology Reports
Issue number9
Publication statusPublished - 1 Sept 2020


  • Absenteeism
  • Ankylosing spondylitis
  • Axial spondyloarthritis
  • Presenteeism
  • Sick leave
  • Work productivity


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