Work of breathing during SIMV with and without pressure support

TY - JOUR

T1 - Work of breathing during SIMV with and without pressure support

AU - Patel, D-S

AU - Rafferty, G. F.

AU - Lee, S.

AU - Hannam, S.

AU - Greenough, A.

PY - 2009/6

Y1 - 2009/6

N2 - Objective: In a randomised trial, pressure support with synchronised intermittent mandatory ventilation (SIMV) compared to SIMV alone was associated with a significant reduction in supplementary oxygen duration. The hypothesis that the addition of pressure support to SIMV compared to SIMV alone would reduce the work of breathing was examined. Design: Prospective study. Setting: Perinatal service. Patients: 20 infants, with a mean gestational age of 31 weeks, being weaned from mechanical ventilation were studied. Interventions: 1 h periods of SIMV and SIMV with pressure support at 50% of the difference between the peak inflating pressure and positive end expiratory pressures. Main outcome measures: The work of breathing was assessed by measurement of the transdiaphragmatic pressure time product (PTPdi). Results: The mean PTPdi on SIMV plus pressure support was 112 cm H2O.s/min, approximately 20% lower than that on SIMV alone (141 cm H2O.s/min) (p

AB - Objective: In a randomised trial, pressure support with synchronised intermittent mandatory ventilation (SIMV) compared to SIMV alone was associated with a significant reduction in supplementary oxygen duration. The hypothesis that the addition of pressure support to SIMV compared to SIMV alone would reduce the work of breathing was examined. Design: Prospective study. Setting: Perinatal service. Patients: 20 infants, with a mean gestational age of 31 weeks, being weaned from mechanical ventilation were studied. Interventions: 1 h periods of SIMV and SIMV with pressure support at 50% of the difference between the peak inflating pressure and positive end expiratory pressures. Main outcome measures: The work of breathing was assessed by measurement of the transdiaphragmatic pressure time product (PTPdi). Results: The mean PTPdi on SIMV plus pressure support was 112 cm H2O.s/min, approximately 20% lower than that on SIMV alone (141 cm H2O.s/min) (p

U2 - 10.1136/adc.2008.152926

DO - 10.1136/adc.2008.152926

M3 - Article

SN - 1468-2044

VL - 94

SP - 434

EP - 436

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

IS - 6

ER -