TY - JOUR
T1 - Wrist-worn actigraphy in agitated late-stage dementia patients
T2 - A feasibility study on digital inclusion
AU - Guu, Ta-Wei
AU - Brem, Anna-Katharine
AU - Albertyn, Christopher P
AU - Kandangwa, Pooja
AU - Aarsland, Dag
AU - Ffytche, Dominic
N1 - Funding Information:
The authors sincerely appreciate the participation of all the patients, their family, and caregivers. The authors also appreciate Ms Simrat Kaur's contribution to the study. The Sativex for the treatment of the Agitation & Aggression in Alzheimer's Dementia (STAND) trial was supported by Alzheimer’s Research UK (Registered Charity No: 207711 (England & Wales), SC041156 (Scotland)), Global Clinical Trials Fund (GCTF). Additional support is supplied from the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. The funders had no role in the trial design, patient recruitment, data collection, analysis, interpretation; nor in writing of the manuscript or the decision to submit it for publication.
Publisher Copyright:
© 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
PY - 2024/5
Y1 - 2024/5
N2 - BACKGROUND: Wrist-worn actigraphy can be an objective tool to assess sleep and other behavioral and psychological symptoms in dementia (BPSD). We investigated the feasibility of using wearable actigraphy in agitated late-stage dementia patients.METHODS: Agitated, late-stage Alzheimer's dementia care home residents in Greater London area (n = 29; 14 females, mean age ± SD: 80.8 ± 8.2; 93.1% White) were recruited to wear an actigraphy watch for 4 weeks. Wearing time was extracted to evaluate compliance, and factors influencing compliance were explored.RESULTS: A high watch-acceptance (96.6%) and compliance rate (88.0%) was noted. Non-compliance was not associated with age or BPSD symptomatology. However, participants with "better" cognitive function (R = 0.42, p = 0.022) and during nightshift (F
1.240, 33.475 = 8.075, p = 0.005) were less compliant. Female participants were also marginally less compliant (F
1, 26 = 3.790, p = 0.062).
DISCUSSIONS: Wrist-worn actigraphy appears acceptable and feasible in late-stage agitated dementia patients. Accommodating the needs of both the patients and their carers may further improve compliance.
AB - BACKGROUND: Wrist-worn actigraphy can be an objective tool to assess sleep and other behavioral and psychological symptoms in dementia (BPSD). We investigated the feasibility of using wearable actigraphy in agitated late-stage dementia patients.METHODS: Agitated, late-stage Alzheimer's dementia care home residents in Greater London area (n = 29; 14 females, mean age ± SD: 80.8 ± 8.2; 93.1% White) were recruited to wear an actigraphy watch for 4 weeks. Wearing time was extracted to evaluate compliance, and factors influencing compliance were explored.RESULTS: A high watch-acceptance (96.6%) and compliance rate (88.0%) was noted. Non-compliance was not associated with age or BPSD symptomatology. However, participants with "better" cognitive function (R = 0.42, p = 0.022) and during nightshift (F
1.240, 33.475 = 8.075, p = 0.005) were less compliant. Female participants were also marginally less compliant (F
1, 26 = 3.790, p = 0.062).
DISCUSSIONS: Wrist-worn actigraphy appears acceptable and feasible in late-stage agitated dementia patients. Accommodating the needs of both the patients and their carers may further improve compliance.
UR - http://www.scopus.com/inward/record.url?scp=85188420383&partnerID=8YFLogxK
U2 - 10.1002/alz.13772
DO - 10.1002/alz.13772
M3 - Article
C2 - 38497216
SN - 1552-5260
VL - 20
SP - 3211
EP - 3218
JO - Alzheimer's & Dementia
JF - Alzheimer's & Dementia
IS - 5
ER -