X-ray mammogram registration: A novel validation method

Research output: Chapter in Book/Report/Conference proceedingConference paper

5 Citations (Scopus)


Establishing spatial correspondence between features visible in x-ray mammograms obtained at different times has great potential to aid assessment of change in the breast and facilitate its quantification. The literature contains numerous non-rigid registration algorithms developed for this purpose, but quantitative estimation of registration accuracy is limited. We describe a novel validation method which simulates plausible mammographic compressions of the breast using all MRI derived finite element model. Known 3D displacements are projected into 2D and test images simulated from these same compressed MR volumes. In this way we call generate convincing images with known 2D displacements with which to validate a registration algorithm. We illustrate this approach by computing the accuracy for a non-rigid registration algorithm applied to mammograms simulated from three patient MR datasets.

Original languageEnglish
Title of host publicationDigital Mammography
EditorsSM Astley, M Brady, C Rose, R Zwiggelaar
Place of PublicationBERLIN
Number of pages8
ISBN (Print)3-540-35625-8, 978-3-540-35625-7
Publication statusPublished - 2006
Event8th International Workshop on Digital Mammography - Manchester
Duration: 18 Jun 200621 Jun 2006

Publication series

NameLecture Notes in Computer Science
ISSN (Print)0302-9743


Conference8th International Workshop on Digital Mammography


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