Xenotransplantation of breast cancers

Massimiliano Cariati; Rebecca Marlow; Gabriela Dontu

doi:10.1007/978-1-61779-080-5_38

Xenotransplantation of breast cancers

Massimiliano Cariati, Rebecca Marlow, Gabriela Dontu

Comprehensive Cancer Centre

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Three experimental systems based on mouse models are currently used to study breast cancer: transgenic mice, carcinogen-induced models, and xenografts of breast cancers. Each of these models has advantages and limitations. This chapter focuses on xenotransplantation of breast cancers and reviews the techniques used so far in establishing this model, the advantages and limitations compared to other experimental systems, and finally, the technical questions that remain to be answered.

Original language	English
Article number	N/A
Pages (from-to)	471-482
Number of pages	12
Journal	Methods in Molecular Biology
Volume	731
Issue number	N/A
DOIs	https://doi.org/10.1007/978-1-61779-080-5_38
Publication status	Published - 2011

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10.1007/978-1-61779-080-5_38

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title = "Xenotransplantation of breast cancers",

abstract = "Three experimental systems based on mouse models are currently used to study breast cancer: transgenic mice, carcinogen-induced models, and xenografts of breast cancers. Each of these models has advantages and limitations. This chapter focuses on xenotransplantation of breast cancers and reviews the techniques used so far in establishing this model, the advantages and limitations compared to other experimental systems, and finally, the technical questions that remain to be answered.",

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AU - Dontu, Gabriela

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AB - Three experimental systems based on mouse models are currently used to study breast cancer: transgenic mice, carcinogen-induced models, and xenografts of breast cancers. Each of these models has advantages and limitations. This chapter focuses on xenotransplantation of breast cancers and reviews the techniques used so far in establishing this model, the advantages and limitations compared to other experimental systems, and finally, the technical questions that remain to be answered.

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DO - 10.1007/978-1-61779-080-5_38

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SN - 1064-3745

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JO - Methods in Molecular Biology

JF - Methods in Molecular Biology

IS - N/A

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ER -

Xenotransplantation of breast cancers

Abstract

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