The relevance of bioinformatics technology has grown dramatically over the last decade due to the fast change in human-centric technologies. Bioinformatics now plays a fundamental role in many significant sectors of everyday life, including health, digital forensics, and applications and digital asset security, by providing authentication and authorisation based on people's unique biometric traits. When assisting technology and information systems, bioinformatics posed queries such as "Why," "What if," and "When," among others. Bioinformatics opens us to a universe of possibilities in various real-life applications. However, bioinformatics comes with its own set of difficulties. The security of bioinformatics algorithms and applications has been a significant source of worry in recent years. On the opposite side of the pillar, the cybercrime arena is expanding daily as current information and cyber security tactics progress. This dissertation aims to investigate, analyse, and resolve information and cyber security challenges arising from typical bioinformatics techniques and their algorithms and compute applications. For calculating cyclic regularities of strings, many algorithms and applications are presented. This dissertation examines privacy and security challenges with structural regularities in strings such as periods and covers, among other things.