Paediatric traumatic brain injury (TBI) often results in poor adaptive function outcomes,contributing to the public health impact of these injuries. The aim of this systematic review was to identify which neuropsychological and neuroimaging factors are associated with adaptive function following paediatric TBI. Database searches were conducted through Ovid Medline, Ovid PsycINFO, Ovid Embase and the WoS Core Collection,alongside manual searches. A total of 3,528 studies were identified, limited to those published between the years 1990 and 2020. Twenty-one publications met inclusion criteria. Findings were synthesised, and quality assessed using a validated tool. The publications reviewed suggest that certain neuropsychological factors, including language, executive functions, processing speed and memory may be important prognostic factors for adaptive outcomes. Literature on neuroimaging factors was sparse,however it highlighted interesting avenues for future research including further exploration of the impact of white matter damage on adaptive function outcomes.However, due to the heterogeneous nature of the studies included and methodological considerations, caution must be taken in interpreting the findings. Further longitudinal work is needed to standardise measures used and identify the underlying mechanisms of poor adaptive function.
| Date of Award | 1 Oct 2021 |
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| Original language | English |
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| Awarding Institution | |
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| Supervisor | Robin Morris (Supervisor) & David J. Sharp (Supervisor) |
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Systematic Literature Review and Empirical Research Project:
Neuropsychological and neuroimaging factors associated with adaptive functioning in paediatric traumatic brain injury - a systematic review;
Neuropsychological and brain network predictors of adaptive functioning following paediatric traumatic brain injury – an empirical research project
De Simoni, S. (Author). 1 Oct 2021
Student thesis: Doctoral Thesis › Doctor of Clinical Psychology