King's College London

• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R. , Ripke, S. , Mattheisen, M. , Trzaskowski, M. , Byrne, E. M. , Abdellaoui, A. , Adams, M. J. , Agerbo, E. , Air, T. M. , Andlauer, T. M. F. , Bacanu, S. , Bækvad-hansen, M. , Beekman, A. F. T. , Bigdeli, T. B. , Binder, E. B. , Blackwood, D. R. H. , Bryois, J. , Buttenschøn, H. N. , Bybjerg-grauholm, J. & 32 others Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F. 1 May 2018 In : Nature Genetics. 50, 5, p. 668-681

  Research output: Contribution to journal › Article

• Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

  Jiang, X. , O'Reilly, P. F. , Aschard, H. , Hsu, Y. H. , Richards, J. B. , Dupuis, J. , Ingelsson, E. , Karasik, D. , Pilz, S. , Berry, DI. , Kestenbaum, B. , Zheng, J. , Luan, J. , Sofianopoulou, E. , Streeten, E. A. , Albanes, D. , Lutsey, P. L. , Yao, L. , Tang, W. , Econs, M. J. & 30 others Wallaschofski, H., Völzke, H., Zhou, A., Power, C., McCarthy, M. I., Michos, E. D., Boerwinkle, E., Weinstein, S. J., Freedman, N. D., Huang, W. Y., Van Schoor, N. M., Van Der Velde, N., Groot, L. C. P. G. M. D., Enneman, A., Cupples, L. A., Booth, S. L., Vasan, R. S., Liu, C. T., Zhou, Y., Ripatti, S., Ohlsson, C., Vandenput, L., Lorentzon, M., Eriksson, J. G., Shea, M. K., Houston, D. K., Kritchevsky, S. B., Liu, Y., Valdes, A. M. & Spector, T. 17 Jan 2018 In : Nature Communications. 9, 1, 260

  Research output: Contribution to journal › Article

• Widespread covariation of early environmental exposures and trait-associated polygenic variation

  Krapohl, E., Hannigan, L. J., Pingault, J-B., Patel, H., Kadeva, N., Curtis, C., Breen, G., Newhouse, S. J., Eley, T. C., O'Reilly, P. F. & Plomin, R. 16 Oct 2017 In : PNAS. 114, 44, p. 11727-11732

  Research output: Contribution to journal › Article

• Multi-polygenic score approach to trait prediction

  Krapohl, E., Patel, H., Newhouse, S., Curtis, C. J., von Stumm, S., Dale, P. S., Zabaneh, D., Breen, G., O'Reilly, P. F. & Plomin, R. 8 Aug 2017 In : Molecular Psychiatry. 23, 5, p. 1368-1374

  Research output: Contribution to journal › Article

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