Research output per year
Research output per year
Personal profile
Research interests
Mendelian and complex disease genetics in neurological diseases (especially motor neuron disease); Epidemiology of motor neuron disease; Genetic statistics; RNA processing genes and proteins; clinical trials; clinical staging in motor neuron disease; clinical phenotyping in motor neuron disease.
Research interests (short)
Mendelian and complex disease genetics and epidemiology in neurological diseases mainly MND.
Education/Academic qualification
Doctor of Philosophy, Genetic risk factors in amyotrophic lateral sclerosis, University of London
Award Date: 1 Jan 1999
Bachelor of Medicine and Bachelor of Surgery, University of Leicester
Award Date: 1 Jan 1989
Keywords
- RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
- neurology, amyotrophic lateral sclerosis, motor neuron disease, ALS, MND
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 11 Sustainable Cities and Communities -
SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A systematic review on Gut Microbiota and ALS: Cause, Consequence or Correlation?
Chakraborty, D., Roy, T., Ngo, S. T., Al-Chalabi, A. & Al Khleifat, A., 12 Mar 2026, (Accepted/In press) In: Frontiers in Neuroscience.Research output: Contribution to journal › Review article › peer-review
File30 Downloads (Pure) -
Classical HLA class II associations with ALS in Kuwait reveal a DR7–DQ2.2 risk haplotype
Dashti , M., AlAbdulghafour, F., Almutairi , O., Mohammad , A., Malik, M. Z., Al-Chalabi, A., Al Khleifat, A. & Al-Mulla, F., 8 May 2026, In: Frontiers in Immunology. 17, p. 1820694 12 p., 1820694.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Downloads (Pure) -
CYP2D6 variants in amyotrophic lateral sclerosis: an association study of risk and survival
Project MinE ALS Sequencing Consortium, 20 May 2026, (E-pub ahead of print) In: Brain : a journal of neurology. awag178.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
CYP2D6 variants in amyotrophic lateral sclerosis: an association study of risk and survival
Vallikivi, J., Maarten Kooyman, M., Consortium, P. M. A. S., Kirby, J., Nigel Leigh, P., Iacoangeli, A., Al-Chalabi, A. & Al Khleifat, A., 18 May 2026.Research output: Working paper/Preprint › Preprint
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Plasma exosomal HERV-K transcripts are increased in amyotrophic lateral sclerosis
Roy, T., Ramesh, M., Nizam, N. A. A., Tandiono, S., Al-Jamal, K. T., Al-Chalabi, A., Iacoangeli, A. & Al Khleifat, A., Dec 2026, In: BMC NEUROSCIENCE. 27, 1, 10 p., 25.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure)
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The MND Register for England, Wales and Northern Ireland - Phase 2
Al-Chalabi, A. (Primary Investigator)
MNDA Motor Neurone Disease Association
1/01/2026 → 31/12/2030
Project: Research
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NIHR Pre-doctoral Fellowship Round 5 Dharti Vasant Kumar
Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/09/2025 → 28/02/2027
Project: Research
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Identifying CSF and blood immune biomarkers of disease progression and response to IL-2 therapy in individuals with new-onset ALS'.
Tree, T. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)
MNDA Motor Neurone Disease Association
1/09/2025 → 31/05/2028
Project: Research
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Virtual Clinical Trial Populations in Motor Neuron Disease
Al-Chalabi, A. (Primary Investigator), Carter, B. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)
7/05/2025 → 5/11/2027
Project: Research
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NIHR Senior Investigator Award - Ammar Al-Chalabi 2
Al-Chalabi, A. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/04/2025 → 31/03/2029
Project: Research
Thesis
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Genetic risk factors in Amyotrophic Lateral Sclerosis
Al-Chalabi, A. (Author), Leigh, N. (Supervisor) & Powell, J. (Supervisor), 1999Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Prizes
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Fellowship of the Academy of Medical Sciences
Al-Chalabi, A. (Recipient), 22 May 2024
Prize: Election to learned society
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Healey Center International Prize for Innovation in ALS
Al-Chalabi, A. (Recipient), 11 Dec 2020
Prize: Prize (including medals and awards)
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